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  • Niraparib and abiraterone acetate plus prednisone for HRR . . .
    We hypothesized that PARP inhibition within 6 months of starting androgen deprivation therapy for metastatic castration-sensitive prostate cancer (mCSPC) could be effective and improve
  • Advanced and metastatic prostate cancer: ESMO Clinical . . .
    This includes metastatic castration-sensitive prostate cancer (mCSPC), non-metastatic castration-resistant prostate cancer (nmCRPC) and metastatic castration-resistant prostate cancer (mCRPC) The management of early-stage disease is covered in the ESMO CPG for local and locoregional prostate cancer 1
  • Prostate Cancer, Version 3. 2026, NCCN Clinical Practice . . .
    The NCCN Guidelines for Prostate Cancer provide a framework on which to base decisions for patients with prostate cancer across the disease spectrum The Guidelines sections included in this article focus on metastatic castration-sensitive prostate cancer (mCSPC), nonmetastatic castration-resistant prostate cancer (CRPC), and metastatic CRPC (mCRPC) For patients with mCSPC, disease
  • Prostate Cancer, Version 3. 2026 - jnccn. org
    Abstract The NCCN Guidelines for Prostate Cancer provide a framework on which to base decisions for patients with prostate cancer across the dis-ease spectrum The Guidelines sections included in this article focus on metastatic castration-sensitive prostate cancer (mCSPC), nonmeta-static castration-resistant prostate cancer (CRPC), and metastatic CRPC (mCRPC) For patients with mCSPC, disease
  • Efficacy and safety of treatments for metastatic castration . . .
    Metastatic prostate cancer that has not previously been treated with ADT is considered to be castration-sensitive prostate cancer (mCSPC)
  • ASPIRE: A randomized phase III trial of androgen deprivation . . .
    ASPIRE: A randomized phase III trial of androgen deprivation therapy (ADT) plus apalutamide (A) with or without docetaxel (D) in metastatic castration-sensitive prostate cancer (mCSPC) stratified by tumor suppressor gene alterations (Alliance A032302)
  • Metastatic Castration-Sensitive Prostate Cancer: Optimizing . . .
    Further incremental progress in the outcome of patients with mCSPC came from the addition of novel agents, docetaxel or abiraterone, to ADT for more aggressive up-front treatment of metastatic prostate cancer
  • Advanced Prostate Cancer Update: Adding PARP Inhibitor To . . .
    Patients with metastatic castration-sensitive prostate cancer (mCSPC), who have specific genetic mutations, were found to have improved survival by using a targeted treatment called PARP inhibitors combined with standard therapy with an androgen receptor (AR) pathway inhibitor The findings came
  • Chemotherapy-Forward Management of Advanced Prostate Cancer . . .
    Taxane chemotherapy remains a durable backbone in advanced prostate cancer, but its clinical value is increasingly determined by timing, sequencing, and deliverability We synthesize pivotal randomized trials and contemporary guidance to provide a chemotherapy-forward framework spanning metastatic castration-sensitive prostate cancer (mCSPC) and metastatic castration-resistant prostate cancer
  • Advanced Prostate Cancer Progression - Know Your Prostate Plan
    Find information about different kinds of advanced prostate cancer, including non-metastatic, metastatic, castration-sensitive, and castration-resistant





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