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  • N-Phenylacetamide - an overview | ScienceDirect Topics
    N-phenylacetamide, also known as acetanilide, is defined as a substituted acetamide that serves as an intermediate in various organic syntheses and was historically used as an antipyretic drug It exhibits stability up to approximately 400°C before decomposing into various compounds, including aniline and acetic acid AI generated definition based on: Pyrolysis of Organic Molecules (Second
  • 2-Phenylacetamide - an overview | ScienceDirect Topics
    For inhibitors of monomeric zinc (II) β-lactamases, there are few examples such as N- (2′-mercaptoethyl)-2-phenylacetamide (16) with Ki being ca 0 1 mM against the monomeric zinc (II) β-lactamase from Bacteroides cereus 130 For dimeric zinc (II) β-lactamases, 4-morpholinoethane sulfonic acid (MES) (17), which is one of Good's buffer compounds, 180 was found to be an inhibitor against B
  • Solubility behavior of 2-phenylacetamide in sixteen pure solvents and . . .
    The results demonstrate that the dissolution of 2-phenylacetamide is a spontaneous and entropy-driven process in the selected solvents The solubility data, correlation models and derived dissolution properties would promote the development of the separation and reaction of 2-phenylacetamide in industry
  • Design, synthesis, and biological assessment of novel 1,2,3-triazole . . .
    In summary, structure-activity relationship (SAR) studies indicated that the biological activity of the triazole-linked N-phenylacetamide-coumarin hybrids 4 5 (a–j) is influenced by the structural features of the 1,2,3-triazole, coumarin, and N-phenylacetamide moieties, as well as by the linker chain length connecting the coumarin and
  • De novo biosynthesis of 2-phenylacetamide in engineered Escherichia . . .
    2-Phenylacetamide is an important bulk chemical, which is widely used in the production of agricultural chemicals, medicines and perfumes For example, 2-phenylacetamide is used as an precursor in the synthesis of the sedative drug phenobarbital, the antibiotic penicillin and the antirheumatoid drug 1- (3,3-diphenylpropyl)-piperidine phenylacetamide [1], [2] In addition, many 2
  • Novel diazen-bis (phenoxy-1,2,3-triazole-N-phenylacetamide) derivatives . . .
    Fourteen derivatives 9a-n were synthesized of this scaffold and their ChE inhibitory effects were evaluated in vitro and in silico Survey on diazen-bis (phenoxy-1,2,3-triazole-N-phenylacetamide) derivatives 9a-n showed that these compounds could be inhibitors for α-amylase and α-glycosidase as two important target enzymes in type-2 diabetes
  • New benzothiazole-indole-1,2,3-triazole-N-phenylacetamide derivatives . . .
    A new series of benzothiazole-indole-1,2,3-triazole-N-phenylacetamide derivatives 9a-m was designed through hybridization of potent cytotoxic pharmaco…
  • N-(benzazol-2-yl)-2-substituted phenylacetamide derivatives: Design . . .
    This work describes the straightforward and efficient one-pot synthesis of a new library of N-(benzazol-2-yl)-2-substituted phenylacetamide derivative…
  • Rational design, synthesis and biological evaluation of novel HIV-1 . . .
    Rational design, synthesis and biological evaluation of novel HIV-1 protease inhibitors containing 2-phenylacetamide derivatives as P2 ligands with potent activity against DRV-Resistant HIV-1 variants





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