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  • How does ondansetron work? | Understanding Its Mechanism
    Serotonin Blockade: Ondansetron blocks serotonin receptors to prevent nausea Rapid Absorption: It is quickly absorbed, reaching peak levels in 1-2 hours Multiple Uses: Effective for CINV, PONV, and nausea from radiation therapy
  • Antiemetics, Selective 5-HT3 Antagonists - StatPearls - NCBI . . .
    Selective serotonin receptor (5-HT3) antagonists block serotonin, specifically targeting gastrointestinal (GI) vagal nerve terminals and the chemoreceptor trigger zone within the central nervous system
  • Zofran Patient Tips: 7 things you should know - Drugs. com
    Zofran is a selective 5‑HT3 receptor antagonist, and the neurotransmitter, serotonin, appears to play a role in ondansetron's effect Cytotoxic chemotherapy appears to be associated with the release of serotonin from the enterochromaffin cells of the small intestine and the released serotonin may stimulate the vagal afferents through the 5
  • Ondansetron (ZOFRAN ODT) for nausea | ChemoExperts
    Ondansetron (Zofran®) binds to 5HT3 receptors instead of serotonin, and thereby stops the reflex to vomit Ondansetron is given by mouth or IV (in the vein, intravenously) to both prevent and treat nausea and vomiting from chemotherapy, or other causes of nausea
  • Ondansetron for sickness - Patient
    Ondansetron works by blocking serotonin from acting on the receptors, and this stops you from feeling sick or being sick (vomiting) Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken
  • Ondansetron: MedlinePlus Drug Information
    Ondansetron is used to prevent nausea and vomiting caused by cancer chemotherapy, radiation therapy, and surgery Ondansetron is in a class of medications called serotonin 5-HT 3 receptor antagonists It works by blocking the action of serotonin, a natural substance that may cause nausea and vomiting How should this medicine be used?
  • How Does Zofran Work? | Zofran Uses - Healthgrades
    Zofran (ondansetron) is an antiemetic, or antinausea drug It belongs to a class called serotonin 5-HT3 receptor antagonists It works by blocking the action of serotonin This disrupts nausea signals between the brain and gut Zofran uses include preventing nausea from cancer chemotherapy, radiation therapy, and surgery Was this helpful?





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